Article
Blurring cis and trans in gene regulation.
Cell - 28 Jul 2006
Savarese Fabio, Grosschedl Rudolf
Abstract excerpt
In this issue of Cell, Axel and colleagues (Lomvardas et al., 2006) report that a single enhancer of an odorant receptor (OR) gene cluster interacts with multiple OR gene promoters on different chromosomes. This study suggests a mechanism that allows olfactory sensory neurons to choose randomly and express only one out of more than 1000 OR genes.
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