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Article

Prognostic and oncogenic relevance of TLX1/HOX11 expression level in T-ALLs.

Blood - 1 Oct 2007

Bergeron Julie, Clappier Emmanuelle, Radford Isabelle, Buzyn Agnès, Millien Corinne, Soler Gwendoline, Ballerini Paola, Thomas Xavier, Soulier Jean, Dombret Hervé, Macintyre Elizabeth A, Asnafi Vahid

Abstract excerpt

TLX1 is a homeodomain transcription factor generally associated with a favorable outcome in T-cell acute lymphoblastic leukemia (T-ALL). However, the molecular mechanisms of TLX1 deregulation remain unclear and various transcript levels in the absence of 10q24 abnormalities have been reported. A reproducible and accurate delineation of TLX1(+) T-ALL will be necessary for proper therapeutic stratification. We have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17609427
DOI: 10.1182/blood-2007-04-079988

Genes

TLX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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