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Article

Genetic rearrangements in relation to immunophenotype and outcome in T-cell acute lymphoblastic leukaemia.

Best practice & research. Clinical haematology - 1 Sept 2010

Meijerink Jules P P

Abstract excerpt

Mutually exclusive oncogenic rearrangements may delineate specific T-cell acute lymphoblastic leukaemia (T-ALL) subgroups, and so far at least 4 molecular-cytogenetic subgroups have been identified, i.e. the TAL/LMO, the TLX1/HOX11, the TLX3/HOX11L2 and the HOXA subgroups. A fifth group with an immature immunophenotype that can be predicted by an early T-cell precursor signature has also been identified, and has...

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Share to Basic Helix-Loop-Helix Transcription Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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Source

Identifiers

PMID: 21112032
DOI: 10.1016/j.beha.2010.08.002

Genes

TLX1
TLX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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