Article
Association of pre-S deletion mutant of hepatitis B virus with risk of hepatocellular carcinoma.
Journal of gastroenterology and hepatology - 1 Jul 2007
Lin Chih-Lin, Liu Chen-Hua, Chen Wendy, Huang Wen-Ling, Chen Pei-Jer, Lai Ming-Yang, Chen Ding-Shinn, Kao Jia-Horng
Abstract excerpt
BACKGROUND: Pre-S deletion mutant of hepatitis B virus (HBV) affects the expression of middle and small surface proteins, resulting in intracellular accumulation of large surface protein. The correlation between pre-S deletion mutant and risk of hepatocellular carcinoma (HCC) in hepatitis B virus carriers remains unclear. METHODS: Using molecular assays, pre-S deletion mutant of HBV were determined in 266...
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