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Article

Pre-s mutation is a significant risk factor for hepatocellular carcinoma development: a long-term retrospective cohort study.

Digestive diseases and sciences - 1 Mar 2013

Sinn Dong Hyun, Choi Moon Seok, Gwak Geum-Youn, Paik Yong-Han, Lee Joon Hyeok, Koh Kwang Cheol, Paik Seung Woon, Yoo Byung Chul

Abstract excerpt

BACKGROUND: Several cross-sectional studies have shown an association between pre-S mutation and hepatocellular carcinoma (HCC). AIMS: We aim to verify whether pre-S mutation represents a risk for HCC development in a longitudinal way. METHODS: A total of 195 patients with chronic HBV infection [age: 43.7 ± 10.8 years, males: 141 (72.3 %), genotype C: 195 (100 %), hepatitis B e antigen (HBeAg) positive: 109...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Viral

Share to Hepatitis B virus

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Source

Identifiers

PMID: 23053886
DOI: 10.1007/s10620-012-2408-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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