Article
Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16.
The American journal of psychiatry - 1 Jul 2007
Jones Ian, Hamshere Marian, Nangle Jeanne-Marrie, Bennett Philip, Green Elaine, Heron Jess, Segurado Ricardo, Lambert David, Holmans Peter, Corvin Aiden, Owen Mike, Jones Lisa, Gill Michael, Craddock Nick
Abstract excerpt
OBJECTIVE: Vulnerability to the triggering of bipolar episodes by childbirth aggregates in families and may define a genetically relevant subtype of bipolar disorder. The authors conducted a search by systematic whole genome linkage scan for loci influencing vulnerability to bipolar affective puerperal psychosis. METHOD: The authors selected families with bipolar disorder from their previous bipolar disorder...
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