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Article

A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations.

Journal of virological methods - 1 Nov 2007

Middleton Tim, He Yupeng, Pilot-Matias Tami, Tripathi Rakesh, Lim Ben Hock, Roth Andrew, Chen Chih-Ming, Koev Gennadiy, Ng Teresa I, Krishnan Preethi, Pithawalla Ron, Mondal Rubina, Dekhtyar Tatyana, Lu Liangjun, Mo Hongmei, Kati Warren M, Molla Akhteruzzaman

Abstract excerpt

Hepatitis C virus (HCV) replicon-based shuttle vectors that permit phenotypes of NS5B polymerase genes from a large number of patient isolates to be rapidly assessed when transiently expressed in cultured cells were designed. When used to test responses to an inhibitor of HCV RNA-dependent RNA po...

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Identifiers

PMID: 17604129
DOI: 10.1016/j.jviromet.2007.05.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17604129-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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