Article
L-carnosine, a substrate of carnosinase-1, influences glucose metabolism.
Diabetes - 1 Oct 2007
Sauerhöfer Sibylle, Yuan Gang, Braun Gerald Stefan, Deinzer Martina, Neumaier Michael, Gretz Norbert, Floege Jürgen, Kriz Wilhelm, van der Woude Fokko, Moeller Marcus Johannes
Abstract excerpt
OBJECTIVE: Carnosinase 1 (CN1) is a secreted dipeptidase that hydrolyzes L-carnosine. Recently, we have identified an allelic variant of human CN1 (hCN1) that results in increased enzyme activity and is associated with susceptibility for diabetic nephropathy in human diabetic patients. We therefo...
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