Article
Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Apr 2001
Menko A S, Kreidberg J A, Ryan T T, Van Bockstaele E, Kukuruzinska M A
Abstract excerpt
Mammalian submandibular gland (SMG) development leads to the establishment of highly organized secretory acinar and nonsecretory ductal epithelial cells. The ability of maturing salivary epithelial cells to attain their differentiated state has been shown to depend, in part, on interactions between extracellular matrix (ECM) proteins and their integrin receptors. In a search for key regulators of salivary cell...
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