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Laminins and their roles in mammals

24 Jan 2008

Abstract excerpt

Laminins are alpha-beta-gamma heterotrimeric components of all basement membranes. Laminins are now known to play the central role in organizing and establishing the basement membrane. The diversity of laminins allows them to impart special structural and signaling properties to the basement membrane. Of the 12 known laminin chain genes, 10 have been either found to be mutated in humans or experimentally mutated...

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PMID: 18219670
DOI: 10.1002/jemt.20563

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