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Article

Ser252Trp mutation in fibroblast growth factor receptor 2 promotes branching morphogenesis in mouse salivary glands.

Journal of oral biosciences - 1 Mar 2024

Iwata Daiki, Kometani-Gunjigake Kaori, Nakao-Kuroishi Kayoko, Mizuhara Masahiro, Nakatomi Mitsushiro, Moriyama Keiji, Ono Kentaro, Kawamoto Tatsuo

Abstract excerpt

OBJECTIVES: The purpose of this study was to perform morphological and immunohistochemical (IHC) analysis of the submandibular glands (SMGs) in early development in Apert syndrome model mice (Ap mice). METHODS: ACTB-Cre homozygous mice were mated with fibroblast growth factor receptor 2 (Fgfr2+/Neo-S252W) mice; ACTB-Cre heterozygous mice (ACTB-Cre mice) at embryonic day (E) 13.5 served as the control group, and...

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Source

Identifiers

PMID: 38246420
DOI: 10.1016/j.job.2024.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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