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Functional Diversity of Laminins

11 Oct 2012

Abstract excerpt

Laminins are a large family of conserved, multidomain trimeric basement membrane proteins that contribute to the structure of extracellular matrix and influence the behavior of associated cells, such as adhesion, differentiation, migration, phenotype stability, and resistance to anoikis. In lower organisms such as Hydra there is only one isoform of laminin, but higher organisms have at least 16 trimeric isoforms...

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PMID: 23057746
DOI: 10.1146/annurev-cellbio-101011-155750

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