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Article

Specific interactions of serpins in their native forms attenuate their conformational transitions.

Protein science : a publication of the Protein Society - 1 Aug 2007

Na Yu-Ran, Im Hana

Abstract excerpt

Plasminogen activator inhibitor-1 (PAI-1) belongs to the serine protease inhibitor (serpin) protein superfamily. Serpins are unique in that their native forms are not the most thermodynamically stable conformation; instead, a more stable, latent conformation exists. During the transition to the l...

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Identifiers

PMID: 17600149
DOI: 10.1110/ps.072838107
PMCID: PMC2203359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17600149-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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