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Article

The native metastability and misfolding of serine protease inhibitors.

Protein and peptide letters - 1 Jul 2005

Cho Ye-Lim, Chae Young Kee, Jung Chan-Hun, Kim Min-Jung, Na Yu-Ran, Kim Yang-Hee, Kang Shin-Jung, Im Hana

Abstract excerpt

The native metastability of serine protease inhibitors (serpins) is believed to facilitate the conformational change required for biological function. However, energetically unfavorable structural features that contribute to metastability of the native serpin conformation, such as buried polar gr...

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Identifiers

PMID: 16029161
DOI: 10.2174/0929866054395365

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16029161-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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