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Article

Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 18 Aug 2010

Napolitano Francesco, Bonito-Oliva Alessandra, Federici Mauro, Carta Manolo, Errico Francesco, Magara Salvatore, Martella Giuseppina, Nisticò Robert, Centonze Diego, Pisani Antonio, Gu Howard H, Mercuri Nicola B, Usiello Alessandro

Abstract excerpt

Attention deficit/hyperactivity disorder (ADHD) is characterized by inattention, impulsivity, and motor hyperactivity. Several lines of research support a crucial role for the dopamine transporter (DAT) gene in this psychiatric disease. Consistently, the most commonly prescribed medications in ADHD treatment are stimulant drugs, known to preferentially act on DAT. Recently, a knock-in mouse [DAT-cocaine...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20720111
DOI: 10.1523/JNEUROSCI.1682-10.2010
PMCID: PMC6633484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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