Article
Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 18 Aug 2010
Napolitano Francesco, Bonito-Oliva Alessandra, Federici Mauro, Carta Manolo, Errico Francesco, Magara Salvatore, Martella Giuseppina, Nisticò Robert, Centonze Diego, Pisani Antonio, Gu Howard H, Mercuri Nicola B, Usiello Alessandro
Abstract excerpt
Attention deficit/hyperactivity disorder (ADHD) is characterized by inattention, impulsivity, and motor hyperactivity. Several lines of research support a crucial role for the dopamine transporter (DAT) gene in this psychiatric disease. Consistently, the most commonly prescribed medications in AD...
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