Article
Transforming growth factor-beta as a differentiating factor for cultured smooth muscle cells.
The European respiratory journal - 1 Oct 2007
Gawaziuk J P, X, Sheikh F, Cheng Z-Q, Cattini P A, Stephens N L
Abstract excerpt
The aim of the present study was to determine whether the development of supercontractile smooth muscle cells, contributing to the nonspecific hyperreactivity of airways in asthmatic patients, is due to transforming growth factor (TGF)-beta. In cultured smooth muscle cells starved by removal of 10% foetal bovine serum for 7 days, growth arrest was seen; 30% became elongated and demonstrated super contractility....
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