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Cytoskeletal remodeling in differentiated vascular smooth muscle is actin isoform dependent and stimulus dependent

3 Jul 2008

Abstract excerpt

Dynamic remodeling of the actin cytoskeleton plays an essential role in the migration and proliferation of vascular smooth muscle cells. It has been suggested that actin remodeling may also play an important functional role in nonmigrating, nonproliferating differentiated vascular smooth muscle (dVSM). In the present study, we show that contractile agonists increase the net polymerization of actin in dVSM, as...

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PMID: 18596213
DOI: 10.1152/ajpcell.00174.2008

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