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EGFR gene copy number alterations in primary cutaneous malignant melanomas are associated with poor prognosis

26 Jun 2007

Abstract excerpt

Copy number alterations of the epidermal growth factor receptor (EGFR) gene have been extensively analyzed in different cancers, but no data are available for primary malignant melanoma. The aim of the present study was to simultaneously investigate the EGFR gene and chromosome 7 copy number alterations in 81 cutaneous malignant melanomas by interphase FISH and correlate the data with clinicopathological...

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PMID: 17594688
DOI: 10.1002/ijc.22928

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