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Article

Characterization of candidate gene copy number alterations in the 11q13 region along with BRAF and NRAS mutations in human melanoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2009

Lázár Viktória, Ecsedi Szilvia, Szöllosi Attila G, Tóth Réka, Vízkeleti Laura, Rákosy Zsuzsa, Bégány Agnes, Adány Róza, Balázs Margit

Abstract excerpt

Amplification of the 11q13 chromosomal region is a common event in primary melanomas. Several candidate genes are localized at this sequence; however, their role in melanoma has not been clearly defined. The aim of this study was to develop an accurate method for determining the amplification pattern of six candidate genes that map to this amplicon core and to elucidate the possible relationship between BRAF,...

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Source

Identifiers

PMID: 19633643
DOI: 10.1038/modpathol.2009.109

Genes

CCND1
NRAS
BRAF
FGF19
FGF3
FGF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Characterization of candidate gene copy number alterations in the 11q13 region along with BRAF and NRAS mutations in human melanoma.PMID 19633643Read ↗

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