Article
The TNF-alpha-238G > a single-nucleotide polymorphism protects against memory decline in older adults with type 2 diabetes.
Behavioral neuroscience - 1 Jun 2007
Chui Michael H, Papanikolaou Yanni, Fontaine-Bisson Bénédicte, Turcotte Josée, Wolever Thomas M S, El-Sohemy Ahmed, Chiasson Jean-Louis, Rabasa-Lhoret Remi, Maheux Pierre, Ryan Edmond, Greenwood Carol E
Abstract excerpt
Inflammatory markers predict memory dysfunction in elderly patients, but their contribution to memory deficits in adults with Type 2 diabetes mellitus (T2DM) is less well understood. The present study determined whether specific single-nucleotide polymorphisms in the promoter region of tumor necrosis factor-alpha (TNF-alpha) predict verbal memory in older patients with T2DM. Immediate and delayed verbal memory...
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