Article
Involvement of genes required for synaptic function in aging control in C. elegans.
Neuroscience bulletin - 1 Jan 2007
Shen Lu-Lu, Wang Yang, Wang Da-Yong
Abstract excerpt
OBJECTIVE: To identify new genes required for neurosecretory control of aging in C. elegans. METHODS: In view of the importance of nervous system in aging regulation, we performed the screen for genes involved in the aging regulation from genetic loci encoding synaptic proteins by lifespan assay and accumulation of lipofuscin autofluorescence. We further investigated the dauer formation phenotypes of their...
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