Article
Isolation of microRNA targets by miRNP immunopurification.
RNA (New York, N.Y.) - 1 Aug 2007
Easow George, Teleman Aurelio A, Cohen Stephen M
Abstract excerpt
microRNAs (miRNAs) serve as post-transcriptional regulators of gene expression, by guiding effector complexes (miRNPs) to target RNAs. Although considerable progress has been made in computational methods to identify miRNA targets, only a relatively limited assessment of their ability to function in vivo has been reported. Here we describe an alternative approach to miRNA target identification based on a...
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