Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RISC RNA Sequencing for Context-Specific Identification of In Vivo MicroRNA Targets

29 Oct 2010

Abstract excerpt

RATIONALE: MicroRNAs (miRs) are expanding our understanding of cardiac disease and have the potential to transform cardiovascular therapeutics. One miR can target hundreds of individual mRNAs, but existing methodologies are not sufficient to accurately and comprehensively identify these mRNA targets in vivo. OBJECTIVE: To develop methods permitting identification of in vivo miR targets in an unbiased manner,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Fibrosis and Remodeling
Share to Congenital heart defects research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21030712
DOI: 10.1161/circresaha.110.233528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RISC RNA Sequencing for Context-Specific Identification of In Vivo MicroRNA TargetsPMID 21030712Read ↗

Global MicroRNA Profiling of the Mouse Ventricles during Development of Severe Hypertrophic Cardiomyopathy and Heart FailureSemantic proximity Read ↗

Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.Semantic proximity Read ↗

Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAsSemantic proximity Read ↗

Deep mRNA Sequencing for In Vivo Functional Analysis of Cardiac Transcriptional RegulatorsSemantic proximity Read ↗

Expression Profile of microRNAs Regulating Proliferation and Differentiation in Mouse Adult Cardiac Stem CellsSemantic proximity Read ↗

The Expression of microRNA and microRNA Clusters in the Aging HeartSemantic proximity Read ↗

Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP.Semantic proximity Read ↗

Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function.Semantic proximity Read ↗

MicroRNA profiling during mouse ventricular maturation: a role for miR-27 modulating Mef2c expressionSemantic proximity Read ↗

Mime-seq 2.0: a method to sequence microRNAs from specific mouse cell typesSemantic proximity Read ↗

Analysis of Transcriptome Complexity Through RNA Sequencing in Normal and Failing Murine HeartsSemantic proximity Read ↗

Sexual dimorphisms of mRNA and miRNA in human/murine heart diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.