Article
A novel method combining linkage disequilibrium information and imputed functional knowledge for tagSNP selection.
Human heredity - 1 Jan 2007
Rochat R H, de las Fuentes L, Stormo G, Davila-Roman V G, Gu C Charles
Abstract excerpt
Analyses of high-density SNPs in genetic studies have the potential problems of prohibitive genotyping costs and inflated false discovery rates. Current methods select subsets of representative SNPs (tagSNPs) using information either on potential biologic functionality of the SNPs or on the underlying linkage disequilibrium (LD) structure, but not both. Combining the two types of information may lead to more...
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