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Article

Exclusion of the catechol-o-methyltransferase gene from genes contributing to salt-sensitive hypertension in dahl salt-sensitive rats.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 May 2007

Kajimoto Kazuaki, Hiura Yumiko, Sumiya Toshiki, Yasui Naomi, Okuda Tomohiko, Iwai Naoharu

Abstract excerpt

Catechol-O-methyltransferase (COMT) is an enzyme that inactivates catecholamines. Several studies have suggested that this enzyme may play a role in blood pressure regulation. We previously reported that the expression levels of Comt mRNA in Dahl salt-sensitive (DS) rats were lower than those in Lewis (LEW) rats. However, the physiological significance of this phenomenon has not been investigated. The purpose of...

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Identifiers

PMID: 17587758
DOI: 10.1291/hypres.30.459

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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