Article
Association of genetic polymorphisms of ACADSB and COMT with human hypertension.
Journal of hypertension - 1 Jan 2007
Kamide Kei, Kokubo Yoshihiro, Yang Jing, Matayoshi Tetsutaro, Inamoto Nozomu, Takiuchi Shin, Horio Takeshi, Miwa Yoshikazu, Yoshii Masayoshi, Tomoike Hitonobu, Tanaka Chihiro, Banno Mariko, Okuda Tomohiko, Kawano Yuhei, Miyata Toshiyuki
Abstract excerpt
OBJECTIVES: Genetically hypertensive rats provide an excellent model to investigate the genetic mechanisms of hypertension. We previously identified three differentially expressed genes, Acadsb (short/branched chain acyl-CoA dehydrogenase), Comt (catecholamine-O-methyltransferase), and Pnpo (pyridoxine 5'-phosphate oxidase), in hypertensive and normotensive rat kidneys as potential susceptibility genes for rat...
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