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Article

Catechol-O-methyltransferase and Pregnancy Outcome: an Appraisal in Rat.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Feb 2021

Iqbal Khursheed, Dhakal Pramod, Pierce Stephen H, Soares Michael J

Abstract excerpt

Catechol-O-methyltransferase (COMT) has been shown to be a key regulator of pregnancy outcomes in mouse, and its deficiency is causative in the development of a preeclampsia-like disease process. Preeclampsia is a human pregnancy disorder associated with failure of intrauterine trophoblast cell invasion and trophoblast-guided uterine spiral artery remodeling, which are not well-developed in mouse. The purpose of...

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Identifiers

PMID: 33048315
DOI: 10.1007/s43032-020-00348-7
PMCID: PMC8082470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Catechol-O-methyltransferase and Pregnancy Outcome: an Appraisal in Rat.PMID 33048315Read ↗

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