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Article

A polymorphic GT short tandem repeat affecting beta-ENaC mRNA expression is associated with low renin essential hypertension.

American journal of hypertension - 1 Jul 2007

González Alexis A, Carvajal Cristian A, Riquelme Erick, Krall Paola M, Munoz Carlos R, Mosso Lorena M, Kalergis Alexis M, Fardella Carlos E

Abstract excerpt

BACKGROUND: The epithelial sodium channel (ENaC) is a candidate gene associated with the development of essential hypertension. A potentially polymorphic repetitive region (GT dinucleotide short tandem repeat [STR]) was identified in intron 8 of beta-ENaC gene (SCNN1B). The aim of this study was to identify the prevalence and distribution of a polymorphic GT-STR in SCNN1B in Chilean essential hypertensive (EH)...

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Identifiers

PMID: 17586416
DOI: 10.1016/j.amjhyper.2007.02.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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