Article
Association of CT dinucleotide repeat polymorphism in the 5'-flanking region of the guanylyl cyclase (GC)-A gene with essential hypertension in the Japanese.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jan 2008
Usami Satoru, Kishimoto Ichiro, Saito Yoshihiko, Harada Masaki, Kuwahara Koichiro, Nakagawa Yasuaki, Nakanishi Michio, Yasuno Shinji, Kangawa Kenji, Nakao Kazuwa
Abstract excerpt
Guanylyl cyclase (GC)-A (natriuretic peptide receptor [NPR]-1), the receptor for atrial and brain natriuretic peptide, is important in the regulation of blood pressure in animal models and, possibly, in humans. In this study, we examined the association between dinucleotide repeat polymorphism within the 5'-flanking region of the GC-A gene and essential hypertension in a group of Japanese subjects. By genotyping...
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