Article
Haplotype analysis of the human renin gene and essential hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2003
Hasimu Buaijiaer, Nakayama Tomohiro, Mizutani Yoshihiro, Izumi Yoichi, Asai Satoshi, Soma Masayoshi, Kokubun Shinichiro, Ozawa Yukio
Abstract excerpt
The human renin gene is an attractive candidate for involvement in the underlying cause of essential hypertension (EH). Despite extensive examination, the relation between the renin gene and hypertension remains unclear. The aims of the present study were to discover new genetic markers of EH and to investigate the relations between polymorphisms of the renin gene and EH in the Japanese. Using the polymerase...
Topics
- Adult
- DNA
- Gene Frequency
- Genotype
- Haplotypes
- Humans
- Hypertension
- Middle Aged
- Polymorphism, Single Nucleotide
- Polymorphism, Single-Stranded Conformational
- Renin