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Article

Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project

13 Sept 2012

Abstract excerpt

BACKGROUND: In the INRG dataset, the hypothesis that any segmental chromosomal alteration might be of prognostic impact in neuroblastoma without MYCN amplification (MNA) was tested. METHODS: The presence of any segmental chromosomal alteration (chromosome 1p deletion, 11q deletion and/or chromosome 17q gain) defined a segmental genomic profile. Only tumours with a confirmed unaltered status for all three...

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PMID: 22976801
DOI: 10.1038/bjc.2012.375

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