Article
Association of DISC1 with autism and Asperger syndrome.
Molecular psychiatry - 1 Feb 2008
Kilpinen H, Ylisaukko-Oja T, Hennah W, Palo O M, Varilo T, Vanhala R, Nieminen-von Wendt T, von Wendt L, Paunio T, Peltonen L
Abstract excerpt
The DISC1 gene at 1q42 has generated considerable interest in various psychiatric diseases, since a balanced translocation interrupting the gene was found to cosegregate with schizophrenia and related mental illnesses in a large Scottish pedigree. To date, linkage and association findings to this locus have been replicated in several study samples ascertained for psychotic disorders. However, the biological...
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