Article
Polymorphism C3435T of the MDR1 gene in Central Americans and Spaniards.
Molecular biology reports - 1 Sept 2008
Vicente J, Sinues Blanca, Fanlo A, Vasquez P, Medina J C, Martinez-Jarreta B
Abstract excerpt
The human multidrug resistance gene (MDR1) encodes for P-glycoprotein (P-gp) which is a transmembrane transporter protein that acts as an efflux pump for a number of lypophilic compounds. It plays a protective role for cells against DNA damage. The wobble C3435T polymorphism at exon 26 has been a...
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