Article
Distribution of the functional MDR1 C3435T polymorphism in the Han population of China.
Swiss medical weekly - 10 Jun 2006
Li Yanhong, Wang Yonghua, Sun Jie, Li Yan, Yang Ling
Abstract excerpt
PRINCIPLES: 3435C>T, a single nucleotide polymorphism (SNP) in exon 26 of the MDR1 gene, is linked to the variability of P-gp expression and function among different individuals. It was found that ethnic differences exist in the polymorphism of the MDR1(C3435T) gene. However, the distribution of 3435C>T genotypes in the Chinese Han population is not clear up till now. METHODS: In this study, the polymerase chain...
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