Article
CYP3A5 3, CYP3A4 1B and MDR1 C3435T genotype distributions in Ecuadorians.
Disease markers - 1 Jan 2008
Sinués Blanca, Vicente Jorge, Fanlo Ana, Mayayo-Sinués Esteban, González-Andrade Fabricio, Sánchez-Q Dora, Martínez-Jarreta Begoña
Abstract excerpt
Polymorphisms in CYP3A genes, such as CYP3A5} and CYP3A4, as well as in the MDR1 gene, which encodes for P-glycoprotein, have been implicated as genetic markers in several disorders. Differences in the frequency distribution of the allelic variants CYP3A5 3, CYP3A4 1B, and MDR1 3435T have been demonstrated between distinct ethnic groups. In this study we examined the frequency of these allelic variants in 317...
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