Article
Photodynamic therapy resistant human colon carcinoma HT29 cells show cross-resistance to UVA but not UVC light.
Photochemistry and photobiology - 1 Jan 2000
Zacal Natalie, Rainbow Andrew J
Abstract excerpt
The isolation of photodynamic therapy (PDT)-resistant HT29 human colon adenocarcinoma cells has been reported previously. These PDT-resistant variants show increased expression of the Hsp27 and BNip3 proteins and a decreased expression of mutant p53 protein compared with parental HT29 cells. Because mutant p53 and increased expression of Hsp27 have been associated with resistance to various chemotherapeutic...
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