Article
A single-electrode, dual-potential ferrocene-PNA biosensor for the detection of DNA.
Chembiochem : a European journal of chemical biology - 16 Aug 2010
Hüsken Nina, Gebala Magdalena, Schuhmann Wolfgang, Metzler-Nolte Nils
Abstract excerpt
A Fc-PNA biosensor (Fc: ferrocenyl, C(10)H(9)Fe) was designed by using two electrochemically distinguishable recognition elements with different molecular information at a single electrode. Two Fc-PNA capture probes were therefore synthesized by N-terminal labeling different dodecamer PNA sequences with different ferrocene derivatives by click chemistry. Each of the two strands was thereby tethered with one...
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