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Article

2'-anthraquinone-conjugated oligonucleotide as an electrochemical probe for DNA mismatch.

Bioconjugate chemistry - 1 Jan 2008

Kumamoto Satoshi, Watanabe Mariko, Kawakami Naoko, Nakamura Mitsunobu, Yamana Kazushige

Abstract excerpt

We previously prepared the oligonucleotides (ODNs) conjugated to an anthraquinone (AQ) group via one carbon linker at the 2'-sugar position. When these modified ODNs bind to cDNA sequences, the AQ moiety can be intercalated into the predetermined base-pair pocket of a duplex DNA. In this paper, 2'-AQ-modified ODNs are shown to be an excellent electrochemical probe to clarify the effect of a mismatch base on the...

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Identifiers

PMID: 17988077
DOI: 10.1021/bc070097f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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