Article
[Disorders in thyroid hormone metabolism].
Rinsho byori. The Japanese journal of clinical pathology - 1 Mar 2010
Iwasaki Yasumasa
Abstract excerpt
The levels of the serum thyroid hormone (free T4 and free T3) are determined not only by thyroid hormone synthesis/secretion but also by their metabolism. Thyroid hormone metabolism is mediated by three selenoproteins, selenodeiodinase type 1, 2, and 3 (D1, D2, and D3), the expression and function of which are tightly regulated in a tissue-specific manner. Among them, D2 increases and D3 decreases the...
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