Article
Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints.
BMC developmental biology - 17 Jun 2007
Teppner Ingeborg, Becker Sonja, de Angelis Martin Hrabé, Gossler Achim, Beckers Johannes
Abstract excerpt
BACKGROUND: Expression of the mouse Delta-like 1 (Dll1) gene in the presomitic mesoderm and in the caudal halves of somites of the developing embryo is required for the formation of epithelial somites and for the maintenance of caudal somite identity, respectively. The rostro-caudal polarity of somites is initiated early on within the presomitic mesoderm in nascent somites. Here we have investigated the...
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