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Article

Mouse mutant "rib-vertebrae" (rv): a defect in somite polarity.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2000

Nacke S, Schäfer R, Habré de Angelis M, Mundlos S

Abstract excerpt

The recessive mouse mutant rib-vertebrae (rv) affects the morphogenesis of the axial skeleton. The phenotype is characterized by vertebral defects such as fusion of adjacent segments, hemivertebrae, or open neural arches and rib defects including fusions, forked ribs, and additional ribs. We have analyzed this mutant in detail and are able to show that defective somite patterning underlies the vertebral...

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PMID: 11002339
DOI: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1046>3.0.CO;2-9

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