Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analyses of single nucleotide polymorphisms and haplotype linkage of LOC387715 and the HTRA1 gene in exudative age-related macular degeneration in a Chinese cohort.

Retina (Philadelphia, Pa.) - 1 Jan 2000

Jiang Hua, Qu Yi, Dang Guangfu, Zhang Xiao, Yin Ningning, Zhang Ying, Bi Hongsheng, Pan Xuemei, Xu Xiaoyi, Zhou Fang, Dai Hong

Abstract excerpt

PURPOSE: To investigate the effect of single nucleotide polymorphisms (SNPs) and haplotypes in the genes encoding age-related maculopathy susceptibility 2 (LOC387715/ARMS2) and high-temperature requirement A-1 (HTRA1) in a case-control study in a Chinese cohort of individuals with exudative age-related macular degeneration (AMD). METHODS: We genotyped 2 SNPs, namely, LOC387715 rs10490924 and HTRA1 rs11200638, in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exudates and Transudates
Share to Genetic Linkage
Share to High-Temperature Requirement A Serine Peptidase 1
Share to Homozygote
Share to Macular Degeneration
Share to Odds Ratio
Share to Proteins
Share to Serine Endopeptidases

Source

Identifiers

PMID: 19491722
DOI: 10.1097/IAE.0b013e3181a3b90e

Genes

HTRA1
ARMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analyses of single nucleotide polymorphisms and haplotype linkage of LOC387715 and the HTRA1 gene in exudative age-related macular degeneration in a Chinese cohort.PMID 19491722Read ↗

Association of CFH, LOC387715, and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population.Semantic proximity Read ↗

HTRA1 rs11200638 variant and AMD risk from a comprehensive analysis about 15,316 subjects.Semantic proximity Read ↗

Association of genetic polymorphisms and age-related macular degeneration in Chinese population.Semantic proximity Read ↗

LOC387715/HTRA1 polymorphisms, smoking and combined effects on exudative age-related macular degeneration in a Korean population.Semantic proximity Read ↗

Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.Semantic proximity Read ↗

Analysis of Genetic and Environmental Risk Factors and Their Interactions in Korean Patients with Age-Related Macular DegenerationSemantic proximity Read ↗

High-temperature requirement factor A1 rs11200638 polymorphism and age-related macular degenerative from a comprehensive analysis about 15316 subjectsSemantic proximity Read ↗

Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population.Semantic proximity Read ↗

Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population.Semantic proximity Read ↗

Genotypic influences on severity of exudative age-related macular degeneration.Semantic proximity Read ↗

The Phenotypic Course of Age-Related Macular Degeneration for ARMS2/HTRA1: The EYE-RISK Consortium.Semantic proximity Read ↗

Association of specific genetic polymorphisms with age-related macular degeneration in a northern Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.