Article
Polymorphism in the hMSH2 gene (gISV12-6T > C) is a prognostic factor in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Oct 2007
Hsu Han-Shui, Lee I-Hsuan, Hsu Wen-Hu, Kao Wei-Ting, Wang Yi-Ching
Abstract excerpt
Genetic polymorphisms at the genes involved in mismatch repair may determine individual's susceptibility to cancer initiation and progression. However, the prognostic significance of hMSH2 gIVS12-6T>C polymorphism (T-C substitution at the -6 intronic splice acceptor site of exon 13) in non-small cell lung cancer (NSCLC) remains unclear. Therefore, we investigated the frequency of hMSH2 gIVS12-6T>C polymorphism in...
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