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Article

An intron splice acceptor polymorphism in hMSH2 and risk of leukemia after treatment with chemotherapeutic alkylating agents.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2003

Worrillow Lisa J, Travis Lois B, Smith Alexandra G, Rollinson Sara, Smith Andrew J, Wild Christopher P, Holowaty Eric J, Kohler Betsy A, Wiklund Tom, Pukkala Eero, Roman Eve, Morgan Gareth J, Allan James M

Abstract excerpt

PURPOSE: We sought to determine whether the -6 exon 13 T>C polymorphism in the DNA mismatch repair gene hMSH2 modulates susceptibility to acute myeloid leukemia after therapy and particularly after O(6)-guanine alkylating chemotherapy. We also determined the extent of microsatellite instability (...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12912950

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12912950-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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