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Article

Analysis of the hMSH2 gene variants in head and neck cancer.

DNA and cell biology - 1 Aug 2010

Demokan Semra, Suoglu Yusufhan, Ulusan Murat, Dalay Nejat

Abstract excerpt

The hMSH2 (human MutS homolog 2) gene plays a central role in DNA mismatch repair. Structural variations in the gene may lead to protein instability and deficient mismatch repair. However, the role of polymorphic variants of the hMSH2 gene have not been defined in head and neck cancer. In this study, the roles of three polymorphic variants in the functional domains of the gene were investigated in 166 patients...

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Identifiers

PMID: 20438357
DOI: 10.1089/dna.2009.1013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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