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Article

A polymorphism in the hMLH1 gene (-93G-->A) associated with lung cancer susceptibility and prognosis.

International journal of molecular medicine - 1 Jan 2010

Shih Chuen-Ming, Chen Chih-Yi, Lee I-Hsuan, Kao Wei-Ting, Wang Yi-Ching

Abstract excerpt

Polymorphisms in DNA repair genes may be associated with differences in repair capacity of DNA damage and may thereby influence an individual's susceptibility to lung cancer. We investigated the association between the -93G-->A polymorphism in the mismatch repair hMLH1 gene for its role in the susceptibility and survival of non-small cell lung cancer (NSCLC) patients. Using a case-control study design, 165 NSCLC...

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PMID: 19956916

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