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Article

Analysis of the polymorphism [gIVS12-6T > C] in the hMSH2 gene in lymphoma and leukemia.

Leukemia & lymphoma - 1 Mar 2003

Paz-y-Miño César, Fiallo B Fernanda, Morillo Santiago A, Acosta Andrés, Giménez Patricia, Ocampo Ligia, Leone Paola E

Abstract excerpt

Given the importance of mismatch repairing genes in keeping the genetic stability in cells, any alterations in their structure or function could generate instability in the genome and predispose the development of oncogenic processes. hMSH2 is the principal gene involved in the post-replicating DNA mismatch repair system. In this study, exon 13 of the hMSH2 gene was analyzed in different neoplasias, leukemias and...

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Source

Identifiers

PMID: 12688322
DOI: 10.1080/1042819021000047038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Analysis of the polymorphism [gIVS12-6T > C] in the hMSH2 gene in lymphoma and leukemia.PMID 12688322Read ↗

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The role of the human DNA mismatch repair gene hMSH2 in DNA repair, cell cycle control and apoptosis: implications for pathogenesis, progression and therapy of cancerSemantic proximity Read ↗

An intron splice acceptor polymorphism in hMSH2 and risk of leukemia after treatment with chemotherapeutic alkylating agents.Semantic proximity Read ↗

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hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6Semantic proximity Read ↗

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IVS10+12A>G polymorphism in hMSH2 gene associated with prognosis for patients with colorectal cancer.Semantic proximity Read ↗

Gly322Asp and Asn127Ser single nucleotide polymorphisms (SNPs) of hMSH2 mismatch repair gene and the risk of triple-negative breast cancer in Polish women.Semantic proximity Read ↗

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