Article
Polymorphisms in hMSH2 and hMLH1 and response to platinum-based chemotherapy in advanced non-small-cell lung cancer patients.
Acta biochimica et biophysica Sinica - 15 May 2010
Cheng Hongyan, Sun Ning, Sun Xinchen, Chen Baoan, Li Fan, Feng Jifeng, Cheng Lu, Cao Yuandong
Abstract excerpt
Platinum-based chemotherapeutics are the most common regimens for advanced non-small-cell lung cancer (NSCLC) patients. However, it is difficult to identify platinum resistance in clinical treatment. Genetic factors are thought to represent important determinants of drug efficacy. In this study,...
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