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Differential Expression of the ARF GAP Genes GIT1 and GIT2 in Mouse Tissues

14 Jun 2007

Abstract excerpt

GIT1 and GIT2 belong to the family of ADP-ribosylation factor GTPase-activating proteins (ARF-GAP) and have been implicated in the regulation of G protein-coupled receptor sequestration, cell migration, T-cell activation, neuronal spine formation, and aggregate formation in Huntington's disease. Examination of endogenous GIT protein expression in tissues, however, has been hampered by the lack of GIT2-specific...

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PMID: 17565117
DOI: 10.1369/jhc.7a7207.2007

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