Article
The Drosophila homologue of Arf-GAP GIT1, dGIT, is required for proper muscle morphogenesis and guidance during embryogenesis.
Developmental biology - 1 Jan 2009
Bahri Sami M, Choy Juliana M, Manser Edward, Lim Louis, Yang Xiaohang
Abstract excerpt
GIT1-like proteins are GTPase-activating proteins (GAPs) for Arfs and interact with a variety of signaling molecules to function as integrators of pathways controlling cytoskeletal organization and cell motility. In this report, we describe the characterization of a Drosophila homologue of GIT1, dGIT, and show that it is required for proper muscle morphogenesis and myotube guidance in the fly embryo. The dGIT...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.